Sir David Haslam, CBE
Former Chair, National Institute for Health and Care Excellence (NICE)
Former President, British Medical Association
Healthcare Innovation Accelerator – the Concept to Adoption Engine
Moving healthcare from promising ideas and isolated pilots to validated, adopted and scaled solutions.
Mission10X is more than a healthcare innovation accelerator. The ecosystem identifies, validates, accelerates and scales healthcare solutions that deliver transformational impact, including 2x to 10x improvements and beyond across care delivery, access, efficiency and outcomes in healthcare and life sciences.
Authority and governance
Advised by leaders who have shaped how the world’s most respected healthcare systems work.
Prof Martin Curley
Former Director of Digital Transformation, HSE Ireland
Former Director, Intel Labs Europe
Rahaf Harfoush
UN High-Level Advisory Body on Artificial Intelligence
NYT bestselling author on digital culture
Graham Copeland
Creator of POSSUM, the world’s most-used surgical risk score
400m+ procedures, 46 countries
Hassan Chaudhury
Head of Commercial, Great Ormond Street Hospital
Commercial Director, DATA-CAN (NHS cancer data hub)
Prof Mike Bewick
Former Deputy National Medical Director, NHS England
Worked under Sir Bruce Keogh
Independent healthcare, AI, data, policy and digital transformation experience helps Mission10X focus on evidence, adoption and measurable impact rather than innovation theatre.
The significant challenges facing healthcare are accelerating.
Healthcare does not suffer from a shortage of ideas. It suffers from a shortage of trusted ways to identify, compare, validate, implement and scale the ideas that matter.
Rising pressure
Ageing populations, longer waits, more chronic disease, multi-morbidity and cost pressure are compounding across health systems.
Fragmented incentives
The different elements in healthcare often work independently, with different incentives, evidence standards and success measures.
Adoption failure
Too many promising solutions remain unvalidated, under-implemented or trapped in isolated pilots.
This is what Mission10X does.
Mission10X brings providers, payers, innovators, academic partners, funders and technology partners together to identify, validate, pilot, fund and scale healthcare solutions that can provide measurable real world impact.
Identify
We review applications and scan global innovation, best practice, research, pilots and partner networks to find ideas and solutions with credible potential for step-change impact.
Validate
We assess evidence, claims, safety, usability, workflow fit, regulatory readiness, data protection and measurable impact.
Pilot
We connect solutions to real-world pilot sites, academic partners, providers and payors so evidence is generated in live care settings.
Fund and Support
We connect suitable solutions to the Innovation Fund, Foundation, Venture Studio, sponsors, grants and aligned partners.
Scale and Share Learning
We create implementation playbooks, reference deployments, impact reports and best-practice learning that can travel across systems and territories.
From ideas to evidence
Independent evaluation of clinical safety, usability, data protection, interoperability, workflow fit and measurable impact.
From pilots to adoption
Real world pilot and academic networks that generate reference deployments and implementation learning.
From adoption to scale
Mission-aligned capital, venture studio support, foundation funding, ecosystem partners and global deployment pathways.
Ecosystem design
The Ecosystem – A Unique Approach to Creating Global Impact in Healthcare.
The different elements in healthcare often work independently, with different incentives, evidence standards and success measures. Mission10X for Healthcare was created to address this issue and connect the different elements into one collaborative ecosystem.
“The biggest challenge is trying to sift through technologies to understand which ones are worthy of consideration.”US ‘For Profit’ CEO
Reducing risk, going faster, scaling more effectively.
Far more than an accelerator. This is a healthcare adoption engine.
Our North Star
Mission10X is guided by a simple idea: healthcare innovation should be judged by whether it can create measurable, scalable improvement in real health systems, not by how impressive it looks in a pilot, pitch deck or press release.
- Stay Left: Prioritise prevention, early intervention and proactive care so health systems are not only responding when people are already in crisis.
- Shift Left: Move care closer to home where it is safe, effective and more accessible, reducing pressure on hospitals while improving patient experience.
- 10X Impact: Focus on solutions capable of step-change improvement in outcomes, access, efficiency, quality, safety, equity or cost, not marginal gains.
- Evidence Over Hype: Cut through the noise by prioritising evidence-based, high-impact innovations that can be validated, accredited and adopted at scale.
- Equity and Global Relevance: Support solutions that can reach underserved populations, work across different health system contexts, and remain relevant in the Global South as well as the Global North.
- Practicality With Purpose: Back ideas that can be implemented in real care settings, with the workflow fit, governance, partnerships and operating model needed to create change.
- Accountability: Measure what happens after adoption, report transparently, and keep learning as solutions move from validation to deployment and scale.
These principles help Mission10X select, validate and scale healthcare innovations that are not only promising, but practical, measurable, equitable and capable of changing the curve.
Read the governing principlesFunding, foundation support and ecosystem execution.
The Mission10X model combines mission aligned capital, foundation mechanisms, venture studio support, partner networks and local adoption pathways.
Ecosystem Catalyst
The Ecosystem Catalyst Company:
- Manages the operational development and evolution of the different elements with guidance from the Global Advisory Board.
- Runs the solution and pilot trial accreditation processes, delivering independent, evidence based assessment.
- Builds the ecosystem as part of a local AI and development hub and with global networks, governments, NGOs, corporates, providers, payors and academic partners.
Foundation
The Foundation provides a mechanism to:
- Support ideas, solutions and entrepreneurs through the Venture Studio.
- Allow tax efficient donations.
- Support pilot deployments globally through Program Related Investments.
- Integrate ideas and deal flow from other foundations and networks, for example the Kids Brain Health Network in Canada.
- Receive and manage proposals for research and development.
- Create academic and technical partnerships for projects and programmes.
- Deliver Sustainable Social Enterprises, companies that are not looking for exits but instead continue to operate and deliver impact.
Innovation Fund
The Mission10X Innovation Fund occupies a unique strategic position in the global health innovation landscape. While traditional players optimize for either impact or profit, we exist in the white space where both objectives reinforce each other.
The fund will target innovations and approaches that deliver meaningful benefits, 10X plus where possible, in critical areas such as diagnostic accuracy, cost reduction, length of stay, morbidity and mortality rates.
Solutions supported will need to be relevant in the Global South as well as Global North.
The Ecosystem Catalyst manages the development and evolution of the different elements.
The catalyst company provides the operating engine for partner alignment, solution evaluation, accreditation, reporting and global ecosystem growth.
Manages the operational development and evolution of the different ecosystem elements with guidance from the Global Advisory Board.
Runs solution and pilot trial accreditation processes with an independent, evidence based approach.
Builds local and global partnerships with networks, governments, NGOs, corporates, providers, payors and academic partners.
Supports healthcare reporting and insight generation focused on systemic issues and high impact approaches.
Mission10X Impact Index.
The index provides a transparent scorecard of the impact across the ecosystem.
Track progress
Tracking progress of solutions supported by Mission10X across health systems and categories.
Highlight impact
Highlighting individual innovations and solutions that deliver the greatest measurable impact on outcomes, capacity, equity and cost.
Quantify reach
Quantifying the innovation pipelines and global reach of the ecosystem.
Mission10X Healthcare Reporting
Reporting focuses on uncovering and highlighting insights and systemic issues that exist in healthcare globally.
- Global, regional and specialised reporting on challenges in healthcare and approaches which make a difference.
- Delivery of broader mission-aligned policy approaches and white papers.
- Regular reporting on key trends relative to the critical issues of spiralling costs, quality challenges and workforce stress.
Frequently asked questions.
Clear answers for healthcare leaders, innovators, payers, funders, foundations and partners evaluating Mission10X.
What is Mission10X?
Mission10X is a healthcare innovation accelerator and ecosystem that identifies, validates, pilots, funds, adopts and scales solutions capable of delivering measurable real world healthcare impact.
How is Mission10X different from a traditional accelerator?
Most accelerators are time limited programmes focused on mentorship, founder education, investor readiness and demo day momentum. Mission10X is built as a healthcare adoption engine. It connects evidence review, accreditation, pilot sites, payers, providers, funders, universities, foundations, technology partners and implementation learning so promising solutions can move from credibility to adoption and scale.
Is Mission10X an incubator?
No. Incubators usually support very early ideas and help founders explore whether something could become a viable product. Mission10X is focused on credible solutions, validated approaches and system level problems where there is potential for measurable healthcare impact.
Is Mission10X a prize challenge?
No. Prize challenges are useful for attracting new ideas around a defined problem. Mission10X can learn from challenge methodology, but its role is broader and ongoing. It is designed to connect problem definition, evidence, adoption, funding, pilot learning, accreditation and scaling over time.
What kind of healthcare solutions does Mission10X support?
Mission10X focuses on credible solutions with potential for step change improvement in outcomes, access, cost, capacity, safety, prevention, diagnostics, workflow and care delivery. These may include AI enabled solutions, digital health platforms, clinical tools, operational models, data infrastructure and prevention focused approaches.
Does Mission10X only support AI solutions?
No. AI is an important part of healthcare transformation, but Mission10X is not limited to AI. The priority is measurable impact, responsible deployment, clinical credibility, evidence, workflow fit and the ability to scale in real health systems.
Why does healthcare need a model like Mission10X?
Healthcare has many pilots, vendors, research projects and promising technologies, but too few trusted pathways for comparing, validating, adopting and scaling what works. Mission10X addresses this gap by bringing key ecosystem participants together around evidence, implementation and measurable outcomes.
How does Mission10X assess solutions?
Mission10X assesses evidence, claims, clinical safety, usability, workflow fit, regulatory readiness, data protection, interoperability, procurement readiness and measurable impact. The aim is not just to identify exciting technology, but to understand whether it can work safely and effectively in real care settings.
What makes a solution suitable for Mission10X?
A suitable solution has credible potential for step change impact, a real healthcare problem, evidence or a clear evidence generation pathway, safe deployment assumptions, a defined user or buyer, implementation feasibility and relevance beyond a single isolated site.
How does Mission10X help health systems and providers?
Mission10X helps health systems find higher quality innovation signal, reduce adoption risk, connect with validated solutions, access implementation learning and identify approaches that can improve outcomes, cost, capacity, workforce sustainability and patient experience.
How does Mission10X help innovators?
Mission10X helps innovators understand evidence expectations, strengthen healthcare credibility, access pilot and academic networks, connect with providers and payors, improve market readiness and pursue funding or partnership pathways where appropriate.
How does Mission10X help payors and insurers?
Mission10X helps payors and insurers identify innovations that support prevention, reduced admissions, improved outcomes, better member experience and more sustainable cost structures.
What role do universities and academic partners play?
Academic partners can support evaluation, evidence generation, research design, data analysis, clinical credibility, implementation learning and dissemination of findings across healthcare systems.
What role do foundations and funders play?
Foundations and funders can support pilot deployments, programme related investments, research and development, global health impact, sustainable social enterprises and solutions that may not fit traditional venture capital models.
What is Mission10X accreditation?
Mission10X accreditation is intended to support confidence in solutions and pilot trials by reviewing evidence, implementation readiness, safety, governance and measurable impact. It helps separate credible, adoptable innovation from unsupported claims.
What is the Mission10X Impact Index?
The Mission10X Impact Index is a transparent scorecard for tracking progress of supported solutions, highlighting innovations with measurable impact and quantifying the innovation pipeline and global reach of the ecosystem.
Who should contact Mission10X?
Healthcare providers, payers, innovators, academic partners, funders, foundations, technology partners and policy leaders should contact Mission10X if they want to validate, adopt or scale solutions that can change healthcare outcomes.
Bring a solution, problem or partnership opportunity.
Work with Mission10X to identify what matters, validate what works, fund what is ready and scale healthcare solutions with credible evidence and measurable impact.