The philanthropic engine of the Mission10X healthcare innovation ecosystem. The Foundation funds the pilots, the venture studio, and the research partnerships that turn evidence-backed digital health innovations into care that reaches patients in the Global South and the Global North alike.
The Foundation enables the work that pure venture capital cannot easily do: fund early evidence, support pilots in lower-income settings, create sustainable social enterprises, and help promising healthcare ideas reach clinical readiness.
It is designed for donors, family offices, corporate partners, donor-advised funds, foundations, academics and social entrepreneurs who want healthcare innovation to move from evidence to adoption, not stop at the pilot stage.
The Foundation is not an add-on. It is the piece that lets healthcare innovation move through places where return-seeking capital will not go alone.
Healthcare innovation is broken in a specific way. Advocacy organisations identify the problems but cannot fund the solutions. Venture capital can fund the solutions but only those that promise commercial returns. Foundations write grants but rarely follow a solution through to deployment.
As a result, evidence-backed innovations stall somewhere between the research paper and the patient.
Mission10X was built to close that gap. The Innovation Fund backs solutions where impact and commercial defensibility reinforce each other.
The Foundation does the work the Fund cannot, supporting pilots in lower-income settings, funding sustainable social enterprises, paying for independent evidence generation, and enabling the venture studio that gets early-stage ideas to clinical readiness.
Together, Fund, Foundation and Ecosystem Catalyst form a connected pipeline from discovery to scale.The Foundation makes the rest possible where pure return-seeking capital will not go.
The Foundation operates as a hybrid philanthropic platform, combining grant-making, programme-related investment, venture studio activity and academic partnership.
The Foundation operates a venture studio that takes promising digital health and AI concepts from research insight to clinically ready prototype. The studio draws on the Mission10X ecosystem, including clinical advisors, evidence frameworks, regulatory specialists and pilot sites, to derisk early-stage solutions before they reach the Innovation Fund or commercial investors.
The Foundation deploys Programme-Related Investments, concessionary and repayable funding instruments, to support real-world pilot deployments in lower-income settings where commercial capital will not yet go. PRIs let donors put capital to work twice: the original gift funds the pilot, and returned capital is recycled into the next one.
Individuals and organisations can give to the Foundation through tax-efficient routes including direct gifts, donor-advised funds, corporate philanthropy programmes and legacy giving. The Foundation is structured to accept gifts across multiple jurisdictions.
The Foundation receives and manages proposals for research, methodology development and implementation science, particularly work that strengthens the evidence base for digital health adoption. Academic partners can lead studies that feed directly into the Mission10X accreditation framework.
The Foundation funds named academic partnerships with universities and clinical institutions. Current and emerging collaborations including accelerators in the UK, Sweden, Maynooth University (Ireland) and the Kids Brain Health Network in Canada through Geoffrey Pradella.
Some healthcare innovations are not built to exit. They are built to keep operating in perpetuity, delivering impact at cost-recovery rather than profit. The Foundation supports these Sustainable Social Enterprises, equivalent in spirit to Mozilla, Wikipedia and the Signal Foundation, but in healthcare.
The Foundation funds in line with the Mission10X investment thesis. Innovations are evaluated on their potential to deliver step-change improvements, 2x to 10x and beyond.
The Foundation accepts support from individual donors, family offices, corporate sponsors, donor-advised fund holders and partner foundations.
One-off or multi-year gifts that fund the Foundation’s general programme. Unrestricted gifts give the Foundation flexibility to deploy capital against the highest-leverage opportunities at any given moment.
Donors can direct gifts to a named programme area, for example care closer to home or Global South pilots, or to a named solution category. Restricted gifts are reported against the specified programme outcomes.
The Foundation is designed to receive grants from DAFs at major sponsors including Fidelity Charitable, Schwab Charitable, Vanguard Charitable and the UK Charities Aid Foundation. Grant recommendations can be made through your DAF sponsor.
Organisations can sponsor specific programmes, problem areas or evidence reports, with named recognition in Mission10X outputs, impact reporting and partner communications. Sponsorship is structured around measurable outcomes rather than logo placement.
The Foundation is governed under Mission10X ethical operating principles: evidence-based decision-making, transparent reporting and independent advisory oversight.
The Advisory Board provides independent challenge and assurance across funding decisions. It includes healthcare leaders such as Sir David Haslam, Prof Martin Curley, Rahaf Harfoush, Graham Copeland, Hassan Chaudhury, Prof Mike Bewick and other expert advisors.
Mission10X Health Impact Verified criteria are applied to funded solutions, assessed against clinical safety, data protection, usability, interoperability and measurable impact.
Foundation activity is reported through the Mission10X Impact Index, covering capital deployed, programmes funded, outcomes achieved and lessons learned.
The Foundation is designed to integrate with, not duplicate, other philanthropic initiatives in healthcare. Where another foundation has the network, evidence base or geographic reach, Mission10X partners rather than competes.
Every solution funded by the Foundation is tracked through the Mission10X Impact Index, a public scorecard that records outcomes, capacity gains, equity improvements and cost impact across the ecosystem.
Reporting is designed to be useful to donors, partner foundations and the wider digital health community. The Foundation does not separate good-news reporting from learning. Both are published.
Formation and registration details will be published here when complete.
The Mission10X Foundation is being established as a charitable structure designed to support tax-efficient giving, programme-related investment, venture studio activity and global healthcare innovation pilots.
Registration details, jurisdiction, charity number, company number, registered address and annual reporting details will be added to this page once formation is complete.
The Foundation will operate under documented conflict-of-interest, safeguarding and ethical operating policies, with independent oversight and public reporting.
Tax treatment for donors will depend on donor jurisdiction, gift route and the Foundation’s final legal structure.
Different visitors arrive with different intent. The Foundation is designed to make the next step clear for donors, researchers, foundations, NGOs and ecosystem partners.
Support the Foundation through a one-off gift, DAF grant, multi-year pledge or corporate sponsorship. Restricted and unrestricted gifts are both welcome.
Discuss a giftResearchers, academic partners and social enterprises can apply for venture studio support, pilot funding or research collaboration.
Apply for supportFoundations, NGOs and donor-advised fund platforms can build referral and co-funding partnerships with Mission10X, particularly in the Global South.
Discuss a partnershipJoin the Mission10X Healthcare Impact Charter, a global commitment to evidence-based healthcare innovation.
Read the CharterClear answers for donors, foundations, researchers, social entrepreneurs and healthcare partners.
The Innovation Fund is an impact-first venture vehicle that backs healthcare solutions where impact and financial returns reinforce each other. The Foundation is a philanthropic vehicle that funds the work the Fund cannot, including pilots in lower-income settings, sustainable social enterprises, independent evidence generation, research partnerships and the venture studio. Together they cover the full range of capital needed to take an innovation from concept to adoption.
The Foundation is in the process of being established. Final registration details will be published on this page when formation is complete.
Yes. The Foundation is designed to accept grants from donor-advised funds, including Fidelity Charitable, Schwab Charitable, Vanguard Charitable, the UK Charities Aid Foundation and other major sponsors. Grant recommendations can be made through your DAF sponsor in the standard way.
A Programme-Related Investment is a concessionary, often repayable, funding instrument used by foundations to support mission-aligned work that would not attract commercial capital. PRIs let the Foundation back pilots and ventures in lower-income healthcare settings while preserving the option to recycle returned capital into further programmes.
The venture studio takes early-stage digital health concepts from researchers, clinicians and entrepreneurs, then provides the clinical advice, evidence design, regulatory specialists and pilot connections needed to reach a fundable or deployable state. Successful studio outputs may proceed to the Mission10X Innovation Fund, commercial investors or long-term operation as Sustainable Social Enterprises.
Funding decisions are made under Mission10X Health Impact Verified criteria, assessed against clinical safety, data protection, usability, interoperability, workflow fit and measurable impact, with independent challenge from the Mission10X Advisory Board.
Yes. The Foundation has an explicit Global South and Global North parity posture. Solutions are expected to be relevant in both, and the Foundation is the principal vehicle through which Mission10X supports pilots, partnerships and adaptations in lower-income settings.
Work with Mission10X to fund pilots, evidence generation, venture studio activity, sustainable social enterprises and global healthcare partnerships.